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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GSK3A
All Species:
20
Human Site:
S64
Identified Species:
31.43
UniProt:
P49840
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49840
NP_063937.2
483
50981
S64
G
G
G
V
G
A
S
S
S
G
G
G
P
G
G
Chimpanzee
Pan troglodytes
XP_530044
483
51007
S64
G
G
G
V
G
A
S
S
S
G
G
G
P
G
G
Rhesus Macaque
Macaca mulatta
XP_001104964
483
50993
S64
G
G
G
V
G
A
S
S
S
G
G
G
P
G
G
Dog
Lupus familis
XP_852706
441
48143
T51
K
V
T
T
V
V
A
T
L
G
Q
G
P
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q2NL51
490
51642
S64
G
G
G
V
G
A
S
S
S
G
G
G
P
S
G
Rat
Rattus norvegicus
P18265
483
51008
S64
G
G
G
V
G
A
S
S
S
G
G
G
P
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416557
433
48108
P44
V
T
T
V
V
A
T
P
G
Q
G
P
D
R
P
Frog
Xenopus laevis
NP_001083752
420
46885
S29
S
F
G
S
M
K
V
S
R
D
K
D
G
S
K
Zebra Danio
Brachydanio rerio
NP_001038386
462
50821
N62
T
A
A
V
V
G
S
N
A
G
K
P
G
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18431
1067
114422
S552
A
D
A
D
S
D
G
S
G
E
N
V
K
T
A
Honey Bee
Apis mellifera
XP_392504
434
48445
K45
K
K
D
R
D
G
N
K
V
T
T
V
V
A
T
Nematode Worm
Caenorhab. elegans
Q9U2Q9
362
40864
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZD5
410
46056
A19
M
A
T
K
Q
S
N
A
S
I
C
A
E
K
L
Baker's Yeast
Sacchar. cerevisiae
P38615
370
42986
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.7
85.5
N.A.
93.8
97
N.A.
N.A.
67.9
67.4
71.8
N.A.
33.4
64.1
55.2
N.A.
Protein Similarity:
100
99.7
99.7
86.3
N.A.
95.5
97.7
N.A.
N.A.
74.9
74.5
77.6
N.A.
38
75.1
63.7
N.A.
P-Site Identity:
100
100
100
20
N.A.
93.3
93.3
N.A.
N.A.
20
13.3
20
N.A.
6.6
0
0
N.A.
P-Site Similarity:
100
100
100
33.3
N.A.
93.3
93.3
N.A.
N.A.
26.6
13.3
33.3
N.A.
6.6
6.6
0
N.A.
Percent
Protein Identity:
N.A.
24.4
N.A.
52.8
40.7
N.A.
Protein Similarity:
N.A.
38.1
N.A.
63.7
55.4
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
0
N.A.
26.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
14
14
0
0
40
7
7
7
0
0
7
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
7
7
7
7
7
0
0
0
7
0
7
7
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
7
0
0
7
7
0
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
34
34
40
0
34
14
7
0
14
47
40
40
14
20
34
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% I
% Lys:
14
7
0
7
0
7
0
7
0
0
14
0
7
7
7
% K
% Leu:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
7
% L
% Met:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
14
7
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
7
0
0
0
14
40
0
7
% P
% Gln:
0
0
0
0
7
0
0
0
0
7
7
0
0
0
0
% Q
% Arg:
0
0
0
7
0
0
0
0
7
0
0
0
0
7
7
% R
% Ser:
7
0
0
7
7
7
40
47
40
0
0
0
0
20
7
% S
% Thr:
7
7
20
7
0
0
7
7
0
7
7
0
0
7
7
% T
% Val:
7
7
0
47
20
7
7
0
7
0
0
14
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _